Los Angeles Rams coach Sean McVay is "not sad" he doesn't have to game plan for San Francisco 49ers stars Deebo Samuel and ...

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian McCaffrey and Deebo Samuel.

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

Samuel (calf) won't practice Thursday, Jennifer Lee Chan of NBC Sports Bay Area reports.

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Check out our Rams vs. 49ers how to watch guide to learn when they play and what free live streams are available ahead of ...

49ers GM John Lynch said Friday that Cowing "may get some [opportunities]" in Sunday's game against the Rams, Matt Barrows of The Athletic reports. With RB Christian McCaffrey (Achilles) on injured ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...